2-Chloro-2-methylpropane, also known as tert-butyl chloride (TBC), is an important chemical used in various industrial processes. If you’re working with chemicals or just curious about how this compound is used, you’ve come to the right place. In this article, we’ll explore 2-chloro-2-methylpropane’s properties, common uses, and how to handle it safely.

2-Chloro-2-Methylpropane manufacturer
What is 2-Chloro-2-Methylpropane?
2-Chloro-2-methylpropane, or tert-butyl chloride, is a colourless, flammable liquid that plays a key role in organic chemistry. With the molecular formula C4H9Cl, this compound contains a tert-butyl group bonded to a chlorine atom, making it a type of tertiary alkyl chloride.
Chemical Overview:
- IUPAC Name: 2-Chloro-2-methylpropane
- Common Name: Tert-butyl chloride
- Molecular Formula: C4H9Cl
Key Properties of 2-Chloro-2-Methylpropane
Physical Properties:
- Appearance: Colourless, with a strong, slightly sweet odour.
- Boiling Point: 51.6°C
- Melting Point: -113.1°C
- Density: 0.864 g/cm³ (at 25°C)
- Solubility: Poor in water but dissolves well in organic solvents like acetone and ethanol.
Chemical Properties:
- Reactivity: Tert-butyl chloride easily undergoes nucleophilic substitution reactions, making it useful in organic synthesis.
- Stability: Stable under most conditions, but can be hazardous if exposed to high heat or flame.
Common Uses of 2-Chloro-2-Methylpropane
Tert-butyl chloride has several key uses in industries ranging from chemical production to pharmaceuticals. Here are the most common ones:
1. Chemical Synthesis
Tert-butyl chloride is often used in chemical reactions to introduce a tert-butyl group into other molecules. This helps create compounds like:
- Tert-butyl alcohol, used as a solvent in labs and industrial processes.
- Isobutene, an important ingredient in the production of high-octane gasoline.
2. Solvent for Chemical Reactions
Its non-polar nature makes it a great solvent in processes that require an organic medium. For example, polymerisation reactions often use tert-butyl chloride to help initiate the reaction.
3. Fuel Additives
Tert-butyl chloride is also used in the fuel industry. It helps increase octane ratings, making gasoline burn more efficiently and reducing engine knocking.
4. Pharmaceutical Applications
In the pharmaceutical industry, tert-butyl chloride is used to synthesise certain drug intermediates and other important chemicals. Its ability to form stable compounds is particularly valuable in the production of steroid drugs.
Safety Tips for Handling 2-Chloro-2-Methylpropane
While tert-butyl chloride is useful, it must be handled carefully due to its flammability and toxicity. Here are some important safety guidelines to follow:
1. Wear Protective Equipment
When working with 2-chloro-2-methylpropane, always ensure you’re using personal protective equipment (PPE) such as:
- Safety goggles to protect your eyes.
- Gloves (preferably nitrile) to avoid skin contact.
- Respiratory protection if working in a poorly ventilated area.
2. Use in Well-Ventilated Areas
Always work with tert-butyl chloride in a well-ventilated area or under a fume hood. Prolonged inhalation can lead to headaches, dizziness, and nausea.
3. Avoid Flammable Sources
Tert-butyl chloride is highly flammable, so make sure to keep it away from open flames, sparks, or hot surfaces. Always store it in a cool, dry place.
4. Spill and Emergency Response
If a spill occurs:
- Evacuate the area immediately.
- Contain the spill using absorbent material.
- If skin is exposed, wash thoroughly with soap and water.
Environmental Impact
Handling 2-chloro-2-methylpropane responsibly is essential for minimising its environmental impact. It is a volatile compound, so it must be disposed of according to local hazardous waste guidelines. Avoid letting it contaminate water sources or soil, as it can be harmful to the environment.
FAQs: Your Quick Guide to 2-Chloro-2-Methylpropane
1. What is the difference between 2-chloro-2-methylpropane and tert-butyl chloride?
There is no difference. 2-chloro-2-methylpropane and tert-butyl chloride are the same compound. The name tert-butyl chloride is commonly used in industry, while 2-chloro-2-methylpropane is the IUPAC name.
2. Is tert-butyl chloride safe to use?
Tert-butyl chloride is safe to use when handled correctly. It is toxic and flammable, so proper safety measures like PPE, ventilation, and safe storage should be followed.
3. What happens if I inhale tert-butyl chloride?
Inhaling tert-butyl chloride vapours can cause respiratory irritation, dizziness, and headaches. Prolonged exposure may lead to more serious health effects, so always use it in a well-ventilated space.
4. Can tert-butyl chloride be disposed of easily?
No, it requires proper disposal. You should not pour it down the drain or mix it with general waste. Instead, dispose of it through certified hazardous waste disposal services.
5. Where can I buy 2-chloro-2-methylpropane?
It is available through chemical suppliers and online marketplaces that specialise in industrial chemicals. Make sure to purchase from reputable sources that comply with safety and quality standards.
Conclusion
2-Chloro-2-methylpropane is a highly useful tert-butyl chloride compound in industries like chemicals, pharmaceuticals, and fuel production. By understanding its properties and how to handle it safely, you can ensure both efficient use and minimise risks. Always prioritise safety and environmental responsibility when working with this powerful chemical.